As their final day in court nears, Mateo and Rafael prepare for the worst, while Perry, Della, and Paul work with an unlikely ally to sway the prosecution's hand. Then, after making his closing arguments, Perry faces the consequences of his relentless pursuit of justice.

Dr. Glassman and Dr. Murphy's relationship may be irreparably damaged following a tense moment during surgery. While Dr. Reznick struggles during her parental leave, Dr. Park may just be the one she needs the most.

Jimmy runs through the results of some polls asking election-related questions in Presidential Polls before speaking with guests Kate Beckinsale, Rainn Wilson and Romeo Santos and welcoming musical guest Romeo Santos.

The Knockouts continue with Mega Mentor Reba McEntire.