Cameron and Rhea are performing on different stages in Portland. In this rare chance to see each other, they're still not seeing enough of each other. Cameron realizes she needs a new opener and Rhea realizes she's made enough of a name as herself, so Rhea decides to join Cameron on tour.

Cameron and Rhea are at home between tour dates and use the time to dive into wedding planning! After a miscommunication about whether they should have their friends Dave (Zeke Nicholson) and Frances (Laura Kightlinger) in the wedding party or not, Cameron and Rhea realize they must get on the same page about wedding decisions.

As Cameron and Rhea hit the road, they learn the realities of being two women on tour: They get to celebrate with fans, but they also need to prioritize their safety. Meanwhile, back at Best Bet, Dave guest hosts for Cameron and Rhea and learns that running a show is not as easy as he thought.

Cameron and Rhea realize they both have clutter in their lives. Rhea keeps everything and has a closet overflowing with keepsakes that have outlived their usefulness. Cameron, on the other hand, keeps ex-girlfriends for the sake of familiarity. This comes to a head when Cameron's ex, Brie, moves to Los Angeles. Cameron and Rhea both learn to let go of their past as they embrace their future together.

Leading up to their sets at Best Bet, three female comedians navigate their respective worlds, and we see how their experiences inform their comedy. Then, we find them in the green room, where a somewhat clueless journalist interviews Cameron and Rhea about whether comedy matters.

After Cameron's wedding suit shows up unwearable and Rhea lands a last-minute audition for a TV show, they decide to call off their joint bachelor party. Miranda (Tess Paras), Melina (Janet Varney), Dave, and Frances rush to their aid. The party, though not as anyone planned, turns out better than they could have hoped for.

Cameron preps nervously for her stand-up special, accompanied by her ex-girlfriend Brie who is barely surviving a breakup. Meanwhile, Rhea is having the time of her life on the set of Bob's TV show. Rhea's shoot goes late, however, and she misses opening for Cameron on the biggest day of her career.

Recovering from Rhea letting Cameron down, a mishap at their planned wedding venue throws Cameron and Rhea into a panic. They have 8 hours to forgive each other and find somewhere to get married. The clock is ticking! With the help of their friends, they reimagine their wedding on the same stage where they host Best Bet.