While investigating an elderly woman's murder, Grissom receives a miniature crime scene replica; Greg attends a hearing to ascertain his culpability in a teenager's accidental death.

The men of Seattle Grace go on a camping trip together, Addison and Callie must team up to work on a patient, Meredith assists Sloan with a procedure unlike any she has experienced, and, suspicious of her recent actions at the hospital, Bailey confronts Cristina. A 9-year-old is seen by Cristina after he swallowed Monopoly game pieces. A pregnant 25-year-old, is brought in after she slipped in the shower. She doesn't want medicine to take away the pain from her injury so not to put her baby's growth in jeopardy. Doctors take care of Daniel, a man who wants a sexual reassignment surgery and who now goes under the name Donna. Accompanying Daniel is his wife of the past 10 years, who was surprised to see him want that surgery but, after much struggling, decided to stay by his side.

Live via satellite, Biff walks through a six-acre corn maze in Livermore, California. By the end of the show, Dave asks him if he's scared, prompting Biff to snap back, "It takes a lot more than this to scare me, man."

Sam and Dean investigate the murder of a lawyer and his wife, who claimed to have seen a ghost before they were killed. However, local authorities arrest the Winchesters after looking into their past.

Tonight Stephen welcomes the founder of "FIRST" and President of DEKA Research and Development Corporation, Dean Kamen.

Jan delivers the bad news to Michael that the Scranton Branch is closing. This leads Michael on a quest to keep up the staff's spirits. Meanwhile, everyone imagines what their lives will be like in the wake of the closure.