At Keppler's request Catherine uses a different approach to catch the killer, and in doing so she deceives the rest of the CSI team. The team soon discovers that something is amiss in Catherine’s investigation.
George has become a sex machine. Dr. Bailey has the idea of opening a free clinic. A doctor at Seattle Grace gets proposed to. Addison is avoiding Alex. The Chief officially announces his intention to retire to the administration of Seattle Grace and to Adele. Rumors of Richard's retirement spread throughout the hospital. Two best friends are left with a difficult decision due to an advanced illness. Derek yells at Meredith.
Bill O'Reilly spills the beans on Stephen, and says what he really thought of him on his show. Stephen interviews Coach Bob Mancini of the Saginaw Spirit. And he doesn't like how he stands on the SMU dispute over Bush's library.