Michael and Sara request Henry Pope's help to retrieve the information that will topple The Company.Mahone pins down an escapee. Sucre discovers a new threat while hitchhiking to reunite with Maricruz. T-Bag brings the Hollander family to his home.

On February 19, 2007, Ferguson announced he would do "no Britney Spears jokes", saying "comedy should have a certain amount of joy in it" and that it shouldn't include "attacking the vulnerable." He referenced his 15 years of sobriety and the struggle he had with addiction, almost ending in suicide.