When a has-been boxer is killed, the CSIs must establish which of several life-threatening acts actually killed him.

The attendings vie to be Chief. Two people who haven't slept together before, will. McSteamy's 60-day vow of chastity has a conclusion. We meet a boss, his assistant, and his wife. We also get to see someone being treated in the clinic. Derek has more questions about his relationship with Meredith. The chairman of the hospital board is admitted as patient. Callie confronts Izzie about her relationship with George.

Steve Martin dominates the show, as he interrupts Dave twice, gets a lapdance from a male stripper, plugs his new book, and performs "The Crow" with banjoists Tony Trischka and Bela Fleck. Also, David Cota and his parakeet AJ perform a few tricks for Dave.

Sam and Dean allow themselves to be arrested in order to investigate a series of murders inside a penitentiary. However things get complicated when FBI agent Henricksen shows up to take over their case.

Stephen is unhappy at the fact that Stephanie Colburtle The Turtle did not win The Great Turtle Race, after being bested by another turtle named Billy. He claims Billy is a male, and demands a re-race. (After explaining that one can tell the sex of a turtle by the concavity of its plastron, Stephen says that he checks the plastron on "all [his] dates, and if it's not concave, [he is] outta there."

It's crisis time at Dunder-Mifflin paper after a large quantity of paper is accidentally shipped out with an obscene watermark. Michael attempts to explain the situation to the media while Jim and Andy try to calm down the high school principal who has sent out prom invites on the affected stationary.