When a serial killer eludes capture in Nevada and escapes with his son to New York City, the crew picks up the trail with the help of Las Vegas CSI's Gil Grissom. This is the Without a Trace episode that is part of the two episode crossover story.

(Crossover episode with Without A Trace, Season 6 Episode 6.) Grissom and the team join forces with Jack Malone, an FBI Agent from New York to track a serial killer.

Two arguing parents, who are named Jane and Don, bring their son in because he swallowed coins, while a middle aged woman comes in wanting cosmetic surgery on her chin. A father worries about raising a child alone when the mother needs surgery.

Mac and Dee become vigilantes in order to remove the homeless from their neighborhood, while Frank and Dennis impersonate police officers.

Bela gets in the way yet again as Sam and Dean are investigating multiple victims who drowned even though they were nowhere near water. Sam and Dean make the creepy discovery that the victims all saw a ghost ship right before dying. They tell Bela to stay away, but she's not so willing to leave, as someone's paying her a lot to solve the same case Sam and Dean are investigating.

Michael goes on a survival adventure into the woods - with nothing except the suit on his back - in retaliation of not getting an invite to a similar party from corporate. Back at the office, there is a birthday going on while Jim tries to revolutionize the party.