The murder of a mother and her child seems to be connected to a murder case from 12 years earlier.

Meredith, Cristina and Bailey come to Lexie and Sadie's rescue when a routine surgery goes horribly wrong, as Owen and Derek treat a man seriously injured while sleepwalking and Mark comforts the sleepwalker's distraught daughter.

In the season finale, Charlie gets the gang to help him put together a rock opera based on his song "Nightman."

Stephen Colbert and Kristen Stewart are the scheduled guests.

Adam and Jamie fuel up a couple of SUVs to find out which is more efficient driving with the windows open or the air conditioner on. Next Kari, Tori & Grant try to find the smooth driving on rough roads. Then, can you stop a car by throwing it into reverse? Meanwhile, Adam and Jamie try to sort out several car related myths including using a car as cover in a gunfight and get their hands on their very own Mythbusters Cadillac. Finally, the team tackles the question, what is more dangerous, driving drunk or driving while talking on a cell phone.

"I'll Kill her gentle." The angels want Anna dead, so Sam and Dean go on the run with the frightened girl, determined to discover the secret that has set the furies of Heaven on her.

Tonight Stephen welcomes economist and author of Hot, Flat, and Crowded: Why We Need a Green Revolution--and How It Can Renew America, Thomas Friedman.

Episode info coming soon ..

Oscar has an outburst in the middle of the office and his coworkers start an investigation.

A mysterious person in the office has made a huge mess in the microwave and will not clean it up. Meanwhile, Michael has to come to terms with the fact that there have been certain personnel changes in his staff without his knowing.

Wanted: Tom Dixon/Murder: Gary Simmons Update: Murder: Kimberly Pandelios and Linda Sobek Wanted: Pizza Parlor Killer Legend: Noah's Ark Lost: Wendi Long Mystery: Loews Cottage

Wanted: Sharon Rogers Mystery: Millie MacGregor Update: Wanted: Dennis DePue Wanted: Jerry Gervasoni Wanted: Steven Cox Lost: Christopher Kurowski