As Max pet-sits Randy’s dog, Bruno, and Caroline sets up meetings with actresses who are interested in playing her in the potential biopic, Bruno escapes while a cannibalistic serial killer is loose in their neighborhood.

The team tracks Savage to a small town in Oregon during the 1950s. Upon arrival, they discover there have been a recent string of murders and they suspect Savage is involved. Professor Stein and Sara go undercover at a psychiatric hospital, where Savage is working as a doctor, to find out his plan. While there, Sara meets a nurse named Lindsay and sparks fly. Meanwhile, Ray and Kendra pretend to be a married couple to gain the neighborhood’s trust, but an interracial couple in the ’50s isn’t something that goes unnoticed. Soon, Savage is at their door.

At the urging of Morland’s wealthy associate, Henry Baskerville, Holmes and Watson look into the death of his brother and discover that a witness saw the man chased to his death by a large, glowing animal too fantastic to be real. Sherlock considers intervening when the trauma from the bombing at the morgue negatively impacts ME Hawes’ work.

Meredith, Bailey, Jackson, Callie and Jo travel to a military hospital to perform an extraordinary and extremely risky surgery on a veteran with an advanced tumor. Meanwhile back at Grey Sloan, Andrew is tired of being Maggie’s worst kept secret; Ben makes an impulsive surgical decision; and a team of cheerleaders wreak havoc in the ER.

The Keating 5 are called into questioning by A.D.A Denver about the night Emily Sinclair was murdered. Caleb goes missing as the manhunt for Philip intensifies. In flashback, Annalise’s tactics in the Mahoney case leads to a devastating result.

Portland is declared the most feminist city in the country, and Toni and Candace have to deal with the attention. The town opens a Femi-Mart.

Olivia and the team take on some embattled Secret Service agents. Meanwhile, Abby has her hands full trying to keep Fitz in line, and Jake begins to reveal a few secrets of his own.

Kane searches for a peaceful way to handle things but soon realizes he may be forced to resort to drastic measures. Pike suspects that there may be a leak within the walls of Arkadia. Raven has a plan and reaches out to Jasper for help.

Sheldon works up a contract to split their portion of their guidance system invention royalties, but Bernadette does not like how it's done. Raj must again decide between Emily and Claire when they both contact him.

After leading the JV Girls Volleyball team to the State Championship, Fairbell gets benched when the PTA appoints a new coach. Plus, Shoemaker takes asst. coaching a bit too far, and Loren schemes for a shady game sponsor.

The chefs land in Las Vegas and participate in a high-stakes challenge of cards and cuisine. Later, they must conjure culinary magic for illusionist David Copperfield.

King Aelle goes to Wessex for Christmas and is not impressed with how family relations are developing; Rollo's future hangs in the balance.

Adam, Blake and Ders open a casino in their house.