The repercussions of the revelations come home to roost with public demonstrations, inside insurrection, and fleeing investors. A sudden and mysterious disappearance sends both Axe and Chuck spinning. Connerty, Chuck and the FBI go into manhunt mode. Meanwhile, Lara has to contend with the brotherhood of firefighters who are furious about Axe's behavior—and in an effort to circle the wagons, makes a painful sacrifice.

When a vigilante dressed up as a comic book hero is murdered, Holmes and Watson need to find the man's true identity and find his killer. Also, Morland makes a surprise donation to Watson’s favorite charity, in order to compel her to do him a business-related favor.

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Hannah and her mom, Loreen, embark on a female-empowerment retreat, where Loreen hopes for clarity in her situation with Tad, and Hannah relishes time away from Fran. In Tokyo, Shoshanna enjoys her budding romance with Yoshi, and gets a surprise visitor from the U.S. Jessa meets up with her sister Minerva and asks for a favor.

When Kira forbids K.C. from spending time with her newfound cousin Abby, the teenage spy finds a way around her mom's orders.

While Elizabeth accompanies Alison on a college campus tour, she is ambushed by protestors about a Chilean mining operation involving the U.S. and Chilean governments. Also, Henry, Jane and Jose Campos attempt to track down Jibral Disah's third wife, Hijriyyah.

Hook’s captivity takes a dark turn when Hades threatens to condemn him to the River of Lost Souls after Hook refuses to choose which three of his friends will have to remain in the Underworld. Meanwhile, Gold is suddenly eager to help Emma, Snow, David, Regina, Robin, and Henry find Hook so he can return home to Belle; but in order to do so, he must find his ex-wife Milah in the Underworld and ask for her help. In Fairy Tale Land flashbacks, Rumple and Milah face a life-or-death crisis concerning their son, Baelfire, that forces Rumple to make a deal that will haunt him.

Sean officially moves into the Gallagher house; Fiona plans a traditional wedding; Kev tries to find a way around V and Svetlana's pending green card marriage.

Diane, Cary and Lucca defend the grieving father of a shooting victim (Blair Underwood) in a defamation suit over a billboard he put up describing a gun store owner as a murderer. Also, a romantic rendezvous between Alicia and Jason is interrupted when Alicia learns that Grace is being accused of plagiarizing her college entrance essay.

Two separate groups leave Alexandria for supplies, and while both worry over the future of the community, they will face immediate danger.