April and Andrew consult with a fiery patient who has a giant, inoperable heart tumor. Meanwhile, Alex and Eliza are at odds over the treatment of a young patient, and Stephanie and Ben make decisions that could affect their careers.
As the future of the country hangs in the balance, Olivia and Fitz are at odds with Rowan, and Jake employs surprising tactics to manipulate the Mystery Woman.
Alicia Banes calls Mary for help after her mother, Tasha, goes missing. Sam answers Mary’s phone and he and Dean head out to help Alicia and her twin brother, Max, find their mother who was hunting a powerful witch. Meanwhile, Mary starts to have some doubts about the British Men of Letters.
In the Season 2 finale, Glenn tries to figure out which employees to lay off. Jonah copes with the fallout of an admission he made to Amy. Garrett and Dina spar. Mateo creates an alliance to keep his job. Also: a a tornado warning goes into effect and forces the staff into uncomfortable pairings.
Red sets the Task Force on the trail of a Blacklister with the tools to manipulate memories, causing Liz to question her own experiences. As Gale intensifies his investigation, Ressler receives a new lead on the disappearance of Justice Department official Reven Wright.