Dara O Briain and Hugh Dennis return to the topical comedy show in the company of guests Tom Allen, Angela Barnes, Rhys James, Nigel Ng and Athena Kugblenu.

Sam and Dean are asked to investigate the murder of a childhood friend, calling them back to a motel from their past and perplexing the brothers with a case they thought was solved a long time ago.

Jimmy kicks off the show with a live monologue following Donald Trump and Joe Biden’s final presidential debate, catches up with Julia Louis-Dreyfus and Patton Oswalt and welcomes musical guest Of Monsters and Men.