Patrick's search reaches an epic conclusion. The group reshifts their focus, but a different plan is in store for Hannah.

Terrifying events at Fire Island rupture the group and force them to reconsider everything.

Herrmann is tasked with fulfilling a man's dying wish. Kidd reflects on her Girls on Fire program after one of her students graduates from the Fire Academy. A heckler harasses Firehouse 51.

Courtney and the team regroup after a dramatic confrontation leaves battle lines clearly drawn. A terrifying discovery made by Mike and Jakeem forces Pat and Sylvester to go on high alert. Finally, Paula and Larry take matters into their own hands to make things right.

Under threat, June must find a way to keep herself and her family safe from Gilead and its violent supporters in Toronto.

(Each one should test their own actions. Then they can take pride in themselves alone, without comparing themselves to someone else, 5 for each one should carry their own load.) Ava and Beatrice jump into action when they meet an ally eager to take down a self-proclaimed prophet and his followers. Tragedy strikes at the convent.

(Do not lie to each other, since you have taken off your old self with its practices and have put on the new self, which is being renewed in knowledge in the image of its Creator.) A mysterious nun makes contact with the OCS, while Adriel proposes a partnership to the pope. Lilith turns to an unexpected source for help.

(For there is nothing hidden that will not be disclosed, and nothing concealed that will not be known or brought out into the open.) After the Order sends out an urgent call, Beatrice and Ava connect with old friends in Madrid and stop by a museum. Jillian investigates an anomaly.

(The sacrifices of pagans are offered to demons, not to God, and I do not want you to be participants with demons. You cannot drink the cup of the Lord and the cup of demons too; you cannot have a part in both the Lord’s table and the table of demons.) As a bizarre plague sweeps the city, Ava uncovers new revelations about Miguel – and Adriel’s methods. Lilith explores new possibilities.

(For even the Son of Man did not come to be served, but to serve, and to give his life as a ransom for many.”) Seeking Lilith's whereabouts, the sisters and Miguel visit Jillian. An unnerving discovery upsets Camila. Conflict erupts over Adriel at the conclave.

(Those who hope in the Lord will renew their strength. They will soar on wings like eagles, they will run and not grow weary, they will walk and not be faint.) The Order and their allies prepare for a showdown against Adriel at his new cathedral, but learn their adversaries have been making plans of their own.

(Precious in the sight of the Lord is the death of his faithful servants.) After an intense battle, Ava's halo saves a life, while one of Adriel's followers has a crisis of faith. Camila finds herself behind enemy lines.

(You will seek me and find me when you seek me with all your heart.) Ava visits the other realm and returns with a new plan to end Adriel’s unholy charade – but it will require superhuman strength and painful sacrifices.