Despite his misgivings, Auggie decides to work with Calder on an alternate method to destroy Henry. Joan confronts Auggie about this alliance.

Holmes and Watson find themselves digging through the dark world of the mob to find a killer when they discover the body of a former assassin. Meanwhile, Watson helps a close friend track down a mystery man who swept her off her feet.

Derek and Callie work on a brain mapping project, Richard encourages the interns to use his physical condition as a learning tool and after a discussion with Callie, Meredith considers continuing her mother’s research. Meanwhile, Shane continues to feel guilty about Heather’s death.

Joel seeks boundaries with Peet; Adam and Crosby better their business by setting boundaries with the band; Julia and Camille discover they have something in common; Sarah talks to Ryan and Amber.

When Simon, an English envoy, tells Mary that the English are aware of her fragile engagement to Francis, Mary and Francis put on a show to protect their alliance. Meanwhile, when Queen Catherine learns that someone who knows about her plot to destroy Mary is still alive, she stops at nothing to make sure they are silenced for good.

With Pope & Associates still struggling to find clients, the team decides to take on a philandering senator who enjoys taking photos of his not so public areas. Meanwhile, Mellie gets involved in her own scandal with Democratic Congresswoman Josephine Marcus.

Sheldon's latest scientific breakthrough makes him feel like a fraud – and threatens to haunt him forever. Meanwhile, Howard's romantic gesture to Bernadette causes Penny to step up her game with Leonard.

Girly hats could emasculate the Marines, and Stephen Fry discusses his role in "Twelfth Night".

While Mystic Falls observes its traditional Remembrance Day to honor the dead, Damon and Elena try to help Stefan through a confusing time, a task that ends up taking Elena on an emotional journey of her own. A worried Matt tries to figure out the reason behind his mysterious blackouts, and Caroline makes an effort to get to know Jesse better. Jeremy makes a startling confession that hits Damon hard. Finally, Dr. Maxfield puts a plan in motion that will change everything.

Peter assigns Neal a new handler to investigate an online black market, but Neal’s loyalties will be tested when he discovers the trail might lead to Mozzie.