Spencer gets a surprising offer from Andre; Ricky mulls where to put down roots; Vernon works overtime to return to the field; Charles and Julie clash over his busy schedule.

Madison springs into action when one of the hotel residents gets violent. Meanwhile, Alejandro shows a darker side of himself at the Colonia.

K.C. and Ernie go undercover with a planet-loving group called the Volunteens, while Craig is getting in shape for his new assignment to protect an ambassador.

Masters and Johnson turn to new partners in an effort to put the past behind them and focus on their expanding clinic. Given their fractured triangle, Libby reevaluates her relationship with Bill and Virginia.

Season Finale. Ray, hoping his deal with Hector will be his family's salvation, learns that Sonia has turned over incriminating evidence to FBI agent Frank Barnes. Ray is forced to wear a wire, but decides to play the Russian mob off the FBI, but things take a dangerous turn. Meanwhile, Mickey's attempt to cash in on the big fight leads him to a discovery that could help Ray against both sides.

Things have changed. The infection enters a new phase. Fet wants to celebrate, but Setrakian and Eph are worried there's more work to be done. Justine conscripts a new, unwilling army in the fight while Eichhorst angrily lashes out with a plan to strike back.