Patterson and Rich DotCom take the reigns as the FBI team faces an explosive threat.

Danny and Baez investigate a murder attempt against a celebrated fertility doctor with a seemingly pristine reputation. Also, Eddie is called to intervene in a Reagan family matter involving Danny’s boys; Erin helps Anthony find justice after a date night goes wrong; and Frank ties up loose ends with an old friend.

As Rebecca contemplates her feelings about her career, Paula is forced to deal with a big client. Josh tries to get back in the dating game, while Heather and Hector deal with insurance.

When Oversight’s attempt to capture a drug cartel’s leader goes bad, MacGyver and Jack rush to Mexico to pull their boss out while racing through the heart of the country during Dia de Muertos celebrations. Also, Bozer and Riley use Halloween as a distraction to gather intel on a man accused of treason.

TV host Whoopi Goldberg; professional wrestlers Nikki & Brie Bella; magician Joshua Jay.

Sam comes to realize his dark destiny and tries to groom Mohamad to be a worthy partner. Scab and Ivory are bestowed Daywalker powers and return home to find the Sisterhood in ruins.

Warren and George search for Lt. Dante, who may be part of an underground network helping Talkers flee human vigilantes.